Nicola De Stefano is a full-time Professor of Neurology at the Department of Medicine, Surgery and Neuroscience at the University of Siena, Italy. He is also the Head of the Neuro-Imaging Laboratory in the same Department; and an Honorary Visiting Professor at the Imperial College London, UK. Prof. De Stefano graduated with his MD degree from the University of Siena, Italy, and went on to undertake his internship. After successfully completing his residency in neurology, he went on to pursue postgraduate training overseas in Canada (Montreal Neurological Institure, Montreal) before returning to his alma mater where he obtained his PhD. Subsequently, he covered the position of Adjunct Professor at Montreal Neurological Institute, McGill University, Canada for 12 years, until 2012. His current research interests lie in multiple sclerosis and other neurological diseases involving the brain white matter. In particular, he is a renowned expert on the clinical application of new neuroimaging techniques in brain and muscle of patients with neurological disease. Prof. De Stefano is a member of several prestigious professional societies and organisations. He co-chaired the MAGNIMS European network for 6 years (2009-2016). He has also delivered numerous invited lectures worldwide, and to date, has published numerous books and book chapters as well as more than 330 papers in prestigious international peer-review publications in the area of multiple sclerosis, neurometabolic disorders and neuroimaging.